王文倫醫師: Curriculum Vitae (Wen-Lun Wang, MD, PhD) WFU

2023年3月20日 星期一

Curriculum Vitae (Wen-Lun Wang, MD, PhD)

作者：王文倫


      Wen-Lun Wang, MD, PhD 王文倫 醫師

Current Position
  • Director, Department of Gastroenterology & Hepatology, E-Da Hospital, Kaohsiung, Taiwan
  • Associate Professor, School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan


Education and Professional background
  • 1995-2002  M.D. National Taiwan University, Taipei, Taiwan
  • 2003-2008  Residentship,  National Taiwan University Hospital, Taipei, Taiwan
  • 2009-2015 Ph.D. Institute of Clinical Medicine, National Cheng Kung University, Taiwan
  • 2008-now Attending Physician, E-Da Hospital, Kaohsiung, Taiwan
  • 2019-2023 Chief, Division of Endoscopy, E-Da Hospital, Kaohsiung, Taiwan
  • 2022-now Associate Professor, School of Medicine, College of Medicine, I-Shou   University, Kaohsiung, Taiwan
  • 2022-now Director, Department of Gastroenterology&Hepatology, E-Da Hospital, Kaohsiung, Taiwan

Research Interests
  • Endoscopic diagnosis of early GI tract cancer: Image-enhanced endoscopy;
  • Endoscopic treatment: Radiofrequency ablation, Endoscopic resection;
  • Field cancerization over the upper aerodigestive tract;
  • Biomarkers and Chemoprevention for GI tract cancer;
  • Basic and Clinical GI oncology;
  • Tumor immunology.

Recent Publications
  1. Wen-Lun Wang, I-Wei Chang, Sin-Hua Moi, Ming-Hung Hsu, Chi-Jen Chen, Chao-Tien Hsu, Hsiu-Po Wang, Ching-Tai Lee. Assessment of tumor extension to the ductal system of submucosal glands in patients with superficial esophageal squamous neoplasms: Implications for endoscopic resection. The Journal of Thoracic and Cardiovascular Surgery. 2022;163(6):1951-1960
  2. M. Everson, L. Herrera, Hsiu-Po Wang, Ching-Tai Lee, Chen-Shuan Chung, Ping-Hsin Hsieh, Chien-Chuan Chen, Cheng-Hao Tseng, Ming-Hung Hsu, T.Vercauteren, S. Ourselin, S. Kashin, R. Bisschops, O. Pech, L. Lovat, Wen-Lun Wang* (Co-Corresponding author), R J Haidry. A clinically interpretable convolutional neural network for the real time prediction of early squamous cell cancer of the esophagus; comparing diagnostic performance with a panel of expert European and Asian endoscopists. Gastrointestinal endoscopy 2021; 94:273-281.
  3. Ming-Hung Hsu, Wen-Lun Wang* (Co-Corresponding author), Tzu-Haw Chen, Chi-Ming Tai, Hsiu-Po Wang, Ching-Tai Lee. Long-term outcomes of endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma in Taiwan. BMC Gastroenterol. 2021; 21:308.
  4. I-Chen Wu, Yao-Kuang Wang, Yi-Hsun Chen, Chun-Chieh Wu, Meng-Chieh Wu, Wei-Chung Chen, Wen-Lun Wang, Hung-Shun Lin, Chou-Cheng Chen, Shah-Hwa Chou, Yu-Peng Liu, Ming-Tsang Wu. High Serum Elafin Prediction of Poor Prognosis of Locoregional Esophageal Squamous Cell Carcinoma. Cancers (Basel). 2021;13(12):3082
  5. Jen-Hao Yeh, Chih-Wen Lin, Wen-Lun Wang, Ching-Tai Lee, Jen-Chieh Chen, Chia-Chang Hsu, Jaw-Yuan Wang.Positive Fecal Immunochemical Test Strongly Predicts Adenomas in Younger Adults With Fatty Liver and Metabolic Syndrome. Clin Transl Gastroenterol. 2021;12(2): e00305.
  6. Jen-Hao Yeh , Cheng-Hao Tseng , Ru-Yi Huang , Chih-Wen Lin , Ching-Tai Lee , Po-Jen Hsiao , Tsung-Chin Wu, Liang-Tseng Kuo, Wen-Lun Wang* (Corresponding author). Long-term Outcomes of Primary Endoscopic Resection vs Surgery for T1 Colorectal Cancer: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol 2020; 18:2813-2823
  7. Jen-Hao Yeh, Ru-Yi Huang, Ching-Tai Lee, Chih-Wen Lin, Ming-Hung Hsu, Tsung-Chin Wu, Po-Jen Hsiao, Wen-Lun Wang* (Corresponding author). Long-term outcomes of endoscopic submucosal dissection and comparison to surgery for superficial esophageal squamous cancer: a systematic review and meta-analysis. Ther Adv Gastroenterol 2020; 13: 1–14
  8. Wen-Lun Wang, I-Wei Chang, Ming-Hung Hsu, Tzu-Haw Chen, Chao-Ming Tseng , Cheng-Hao Tseng, Chi-Ming Tai, Hsiu-Po Wang, Ching-Tai Lee. Risk factors and pathological characteristics for intraductal tumor spread of submucosal gland in early esophageal squamous cell neoplasia. Scientific Reports 2020; 10(1):6860
  9. Tseng CM, Wang HH, Lee CT, Tai CM, Tseng CH, Chen CC, Tsai YN, Chen TH, Hsu MH, Wang CC, Hwang TZ, Wang HP, Wang WL* (Corresponding author). A nationwide population-based study to access the risk of metachronous esophageal cancers in head and neck cancer survivors. Scientific Reports 2020;10(1):884
  10. Chao-Ming Tseng, Hsi-Hao Wang, Wen-Lun Wang, Ching-Tai Lee, Chi-Ming Tai, Cheng-Hao Tseng, Chih-Cheng Chen, Ying-Nan Tsai,Meng-Shun Sun, Yao-Chun Hsu. Prognostic Impact of Diabetes Mellitus on Overall Survival in a Nationwide Population-Based Cohort of Patients With Pancreatic Cancer. Endocr Pract. 2020;26(7):707-713
  11. Luis C García-Peraza-Herrera, Martin Everson, Laurence Lovat, Hsiu-Po Wang, Wen Lun Wang, Rehan Haidry, Danail Stoyanov, Sébastien Ourselin, Tom Vercauteren. Intrapapillary capillary loop classification in magnification endoscopy: open dataset and baseline methodology. Int J Comput Assist Radiol Surg. 2020 Apr;15(4):651-659.
  12. Everson M, Herrera L, Li W, Luengo IM, Ahmad O, Banks M, Magee C, Alzoubaidi D, Hsu HM, Graham D, Vercauteren T, Lovat L, Ourselin S, Kashin S, Wang HP, Wang WL*, Haidry RJ* (Joint senior authors). Artificial intelligence for the real-time classification of intrapapillary capillary loop patterns in the endoscopic diagnosis of early oesophageal squamous cell carcinoma: A proof-of-concept study. United European Gastroenterol J. 2019;7(2):297-306
  13. Yeh JH, Hsu MH, Tseng CM, Chen TH, Huang RY, Lee CT, Lin CW, Wang WL* (Corresponding author). The benefit of adding oral simethicone in bowel preparation regimen for the detection of colon adenoma: A systematic review and meta-analysis. Journal of Gastroenterology and Hepatology 2019;34(5):830-836
  14. Wang WL, Chang IW, Chen CC, Chang CY, Tseng CH, Tai CM, Lin JT, Wang HP, Lee CT. Lessons from pathological analysis of recurrent early esophageal squamous cell neoplasia after complete endoscopic radiofrequency ablation. Endoscopy 2018; 50(8):743-750
  15. Wang WL, Chiu YH, Lee CT, Tseng CH, Chen CC, Han ML, Chung CS, Hsieh PH, Chang WL, Wu PH, Hsu WH, Yen HH, Wang HP, Chang CY. A Training Program of a New Simplified Classification of Magnified Narrow Band Imaging for Superficial Esophageal Squamous Cell Carcinoma. Journal of Gastroenterology and Hepatology 2018; 33(6):1248-1255
  16. Wang WL, Chang IW, Chen CC, Chang CY, Tseng CH, Tai CM, Lin JT, Wang HP, Lee CT. The in vivo tissue effect of endoscopic balloon-based radiofrequency ablation in treating esophageal squamous cell neoplasia. United European Gastroenterology Journal 2018; 6(5):656-661
  17. Wang WL, Chang IW, Chen CC, Chang CY, Mo LR, Lin JT, Wang HP, Lee CT. A case series on the use of circumferential radiofrequency ablation for early esophageal squamous neoplasias in patients with esophageal varices. Gastrointestinal endoscopy 2017;85 (2): 322-329
  18. Hsiu-Chi Cheng, Er-Hsiang Yang, Chung-Tai Wu, Wen-Lun Wang, Po-Jun Chen, Meng-Ying Lin, Bor-Shyang Sheu. Hypoalbuminemia is a predictor of mortality and rebleeding in peptic ulcer bleeding under proton pump inhibitor use. J Formos Med Assoc. 2018 Apr;117(4):316-325.
  19. Wu CF, Lee CT, Kuo YH, Chen TH, Chang CY, Chang IW, Wang WL* (Correspondence). High  endothelin-converting enzyme-1 expression independently predicts poor survival of patients with esophageal squamous cell carcinoma. Tumour Biol. 2017;39(9):1010428317725922. 
  20. Wang WL, Chang WL, Yang HB, Wang YC, Chang IW, Lee CT, Chang CY, Lin JT, Sheu BS. Low Disabled-2 expression promotes tumor progression and determines poor survival and high recurrence of esophageal squamous cell carcinoma. Oncotarget  2016; 7 (44): 71169-71181
  21. Wang WL, Chang IW, Chen CC, Chang CY, Lin JT, Mo LR, Wang HP, Lee CT. The spatial predilection for early esophageal squamous cell neoplasia~ a “hot zone” for endoscopic screening and surveillance. Medicine (Baltimore) 2016; 95(15):e3311
  22. Wang WL, Chang IW, Chen CC, Chang WL, Chu YY, Wu PH, Tai WC, Chen PY, Hsieh PH, Chung CS, Chang CY, Lin JT, Wang HP, Lee CT. Predictors for postoperative esophageal stricture after balloon-based radiofrequency ablation for early esophageal squamous neoplasia ~A multicenter validation study. Therapeutic Advances in Gastroenterology 2016; 9(3):257-64
  23. Wang WL, Wang YC, Chang CY, Lo JL, Kuo YH, Hwang TZ, Wang CC, Mo LR, Lin JT, Lee CT. Human papillomavirus infection on initiating synchronous esophageal neoplasia in patients with head and neck cancer. The Laryngoscope 2016; 126(5):1097-102
  24. Wang WL, Chang IW, Chen CC, Chang CY, Lin JT, Mo LR, Wang HP, Lee CT. Radiofrequency ablation versus endoscopic submucosal dissection in treating large early esophageal squamous cell neoplasia. Medicine (Baltimore) 94(49):e2240, 2015
  25. Wang WL, Chang WL, Yang HB, Chang IW, Lee CT, Chang CY, Lin JT, Sheu BS. Quantification of tumor infiltrating Foxp3+ regulatory T cells enables the identification of high-risk patients for developing synchronous cancers over upper aerodigestive tract. Oral oncology 51(7): 698-703, 2015
  26. Wang WL, Wang YC, Lee CT, Chang CY, Lo JL, Hsu YC, Mo LR. The impact of human papillomavirus infection on the survival and treatment response of patients with esophageal cancers. Journal of digestive diseases 16(5): 256-63, 2015
  27. Wang WL, Chang IW, Chang CY, Lin JT, Mo LR, Wang HP, Lee CT. Circumferential balloon-based radiofrequency ablation for ultralong and extensive flat esophageal squamous neoplasia. Gastrointestinal endoscopy 80(6): 1185-9, 2014 
  28. Wang WL, Chang WL, Yeh YC, Lee CT, Chang CY, Lin JT, Sheu BS. Concomitantly elevated serum matrix metalloproteinases 3 and 9 can predict survival of synchronous squamous cell carcinoma of the upper aero-digestive tract. Molecular carcinogenesis 52(6): 438-45, 2013
  29. Wang WL, Wang CP, Wang HP, Lee CT, Chang CY, Tai CM, Tseng CH, Hwang TZ, Wang CC, Lo JL, Tseng PH, Chiu HM, Lee JM, Ko JY, Lou PJ, Wu MS, Lee YC, Lin JT. The benefit of pretreatment esophageal screening with image-enhanced endoscopy on the survival of patients with hypopharyngeal cancer. Oral oncology 49(8): 808-13, 2013 
  30. Wang WL, Lee CT, Lee YC, Hwang TZ, Wang CC, Hwang JC, Tai CM, Chang CY, Tsai SS, Wang CP, Ko JY, Lin JT. Risk factors for developing synchronous esophageal neoplasia in patients with head and neck cancer. Head & neck 33(1): 77-81, 2011 

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